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Summary
Name
GSTM2
Full Name
Glutathione S-transferase Mu 2
Synonyms
GST class-mu 2, GSTM2-2 | GST4
Primary ID
P28161
Links
-
-
Type
protein
Relations
1
Function
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276).
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by mechanism
none
transcriptional regulation
by effect
none
down-regulates quantity by repression
by organism:
none
by tissue:
none
by cell-line
none
Relations
Regulator
Mechanism
target
score
ℹ
+
DNMT3B
down-regulates quantity by repression
transcriptional regulation
GSTM2
0.334
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-271687
pmid
sentence
21246532
Knockdown of Sp1 in normal lung cells reduced GST-M2 expression, and silencing of DNMT-3b increased GST-M2 expression in lung cancer cells.
Publications:
1