Summary

Name LOX
Full Name Protein-lysine 6-oxidase
Synonyms Lysyl oxidase |
Primary ID P28300
Links - -
Type protein
Relations 2
Inhibitors CCT365623 (hydrochloride)
Function Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin (PubMed:26838787). Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding EFEMP2 0.578
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png chemical inhibition LOX 0.8
Publications: 1 Organism: Homo Sapiens