3.0
Summary
| Name |  HMOX2View Modifications |
| Full Name | Heme oxygenase 2 |
| Synonyms | HO-2 | HO2 |
| Primary ID | P30519 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CSNK2A1 | up-regulates activity 
phosphorylation
|
HMOX2 | 0.34 |
| Publications: | 1 | Organism: | Rattus Norvegicus | |
| + | HMOX2 | down-regulates quantity 
chemical modification
|
heme | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | HMOX2 | down-regulates activity
|
HBA1 | 0.258 |
| Publications: | 1 | Organism: | Homo Sapiens | |