| + |
BCOR | down-regulates quantity by repression 
transcriptional regulation
|
HOXA7 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-256013 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 26847029 |
Importantly, our results showed that BCOR is a repressor of HoxA cluster of genes (HoxA5, HoxA7 and HoxA9) in myeloid cells. Knock-down of HoxA5, HoxA7 and HoxA9 significantly decreased the clonogenic growth of Bcor mutant and wild type cells, demonstrating the Hox genes, as targets of BCOR, played an important role in mediating BCOR’s function in regulating myeloid cell proliferation. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
HOXA7 | down-regulates quantity by repression
transcriptional regulation
|
IVL |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254473 |
|
|
Homo sapiens |
Keratinocyte |
| pmid |
sentence |
| 11435435 |
Antisense HOXA7 expression activated transglutaminase 1, involucrin, and keratin 10 message and protein levels, demonstrating that endogenous HOXA7 down-regulates multiple differentiation-specific keratinocyte genes. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
HOXA7 | down-regulates quantity by repression
transcriptional regulation
|
KRT10 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254472 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11435435 |
Antisense HOXA7 expression activated transglutaminase 1, involucrin, and keratin 10 message and protein levels, demonstrating that endogenous HOXA7 down-regulates multiple differentiation-specific keratinocyte genes. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
HOXA7 | down-regulates quantity by repression
transcriptional regulation
|
TGM1 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254474 |
|
|
Homo sapiens |
Keratinocyte |
| pmid |
sentence |
| 11435435 |
Antisense HOXA7 expression activated transglutaminase 1, involucrin, and keratin 10 message and protein levels, demonstrating that endogenous HOXA7 down-regulates multiple differentiation-specific keratinocyte genes. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
KDM6A | up-regulates quantity by expression 
transcriptional regulation
|
HOXA7 |
0.278 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-260024 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 24561908 |
Evidence for direct involvement of UTX in regulation of HOX gene activity was demonstrated through UTX knockdown experiments in HEK293T cells in which loss of UTX induced transcriptional repression of HOXA and HOXC clusters. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
HOXA7
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