Relation Results

Summary

Name HOXA13
Full Name Homeobox protein Hox-A13
Synonyms Homeobox protein Hox-1J | HOX1J
Primary ID P31271
Links - -
Type protein
Relations 3
Function Sequence-specific, AT-rich binding transcription factor which is part of a developmental regulatory system that provides cells with specific positiona ...
View More

Viewer

Type: Score: Layout: SPV 
0.2890.295KDM6AHOXA13EPHA7

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations
Regulator
Mechanism
target
score ℹ
+ KDM6Aup-regulates quantity by expression img/direct-activation.png transcriptional regulation HOXA13 0.289
Identifier Residue Sequence Organism Cell Line
SIGNOR-260022 Homo sapiens
pmid sentence
Evidence for direct involvement of UTX in regulation of HOX gene activity was demonstrated through UTX knockdown experiments in HEK293T cells in which loss of UTX induced transcriptional repression of HOXA and HOXC clusters.
Publications: 1 Organism: Homo Sapiens
+ HOXA13up-regulates quantity by expression img/indirect-activation.png transcriptional regulation EPHA7 0.295
Identifier Residue Sequence Organism Cell Line
SIGNOR-142428 Homo sapiens
pmid sentence
We show that hoxd13 andhoxa13activate transcription from the epha7 promoter and that a mutation of thehoxa13/hoxd13 binding site was sufficient to abolish activation.
Publications: 1 Organism: Homo Sapiens
+ HOXA13up-regulates quantity by expression img/direct-activation.png transcriptional regulation EPHA7 0.295
Identifier Residue Sequence Organism Cell Line
SIGNOR-261631 Mus musculus NG-108-15 Cell
pmid sentence
Analysis of normalized luciferase expression confirmed that wt HOXA13 regulates gene expression through the EphA7 cis-regulatory DNA element
Publications: 1 Organism: Mus Musculus
a simple tooltip