Summary
| Name | CPS1
|
| Full Name | Carbamoyl-phosphate synthase [ammonia], mitochondrial |
| Synonyms | Carbamoyl-phosphate synthetase I, CPSase I | |
| Primary ID | P31327 |
| Links | - - ![]() |
| Type | protein |
| Relations | 6 |
| Pathways | Glutamine metabolism, Nucleotide Biosynthesis |
| Function | Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CPS1 | up-regulates activity
|
Pyrimidine biosynthesis | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Pathways: | Glutamine metabolism | |||
| + | SIRT5 | up-regulates activity
post translational modification
|
CPS1 | 0.508 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | AMPK | down-regulates quantity
|
CPS1 | 0.271 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CPS1 | up-regulates quantity
chemical modification
|
carbamoyl phosphate(2-) | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Pathways: | Glutamine metabolism, Nucleotide Biosynthesis | |||
| + | STK11 | down-regulates quantity
transcriptional regulation
|
CPS1 | 0.296 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CPS1 | down-regulates quantity
chemical modification
|
glutamine | 0.8 |
| Publications: | 1 | Organism: | Homo Sapiens | |
4.0
CPS1



post translational modification
chemical modification