| + |
RPS6KA3 | down-regulates quantity by destabilization 
phosphorylation
|
FOXN2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-273840 |
Ser365 |
EDDPLGDsGYASQPC |
Homo sapiens |
NCI-H1299 Cell |
| pmid |
sentence |
| 29396548 |
Importantly, we identified RSK2 kinase as the upstream kinase for the FOXN2 phosphodegron. The Ser365 and Ser369 sites in a conserved DSGYAS motif are responsible for the ubiquitination of FOXN2 by β-Trcp. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-273841 |
Ser369 |
LGDSGYAsQPCAKIS |
Homo sapiens |
NCI-H1299 Cell |
| pmid |
sentence |
| 29396548 |
Importantly, we identified RSK2 kinase as the upstream kinase for the FOXN2 phosphodegron. The Ser365 and Ser369 sites in a conserved DSGYAS motif are responsible for the ubiquitination of FOXN2 by β-Trcp. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
3.0
FOXN2
- 
- 