Summary

Name ICAM3
Full Name Intercellular adhesion molecule 3
Synonyms ICAM-3, CDw50, ICAM-R
Primary ID P32942
Links - -
Type protein
Relations 2
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) (PubMed:1448173). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590).

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation ICAM3 0.339
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding AD/b2 integrin 0.596
Publications: 1