Summary

Name CD68
Full Name Macrosialin
Synonyms Gp110 |
Primary ID P34810
Links - -
Type protein
Relations 4
Function Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

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Relations

Regulator Mechanism target score ℹ
+ IRF8down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation CD68 0.287
Publications: 1 Organism: Mus Musculus
+ ELF1up-regulates quantity by expression img/indirect-activation.png transcriptional regulation CD68 0.2
Publications: 1 Organism: Mus Musculus
+ SPI1down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation CD68 0.336
Publications: 1 Organism: Mus Musculus
+ IRF4down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation CD68 0.305
Publications: 1 Organism: Mus Musculus