| + |
MKX | up-regulates quantity by expression 
transcriptional regulation
|
SOX5 |
0.299 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267214 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 33115953 |
MKX is a meniscus-enriched transcription factor. In human meniscus cells, MKX regulates the expression of meniscus marker genes, OA-related genes, and other transcription factors, including Scleraxis (SCX), SRY Box 5 (SOX5), and Runt domain-related transcription factor 2 (RUNX2). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Meniscus |
| + |
SOX5 | up-regulates quantity by expression 
transcriptional regulation
|
COL2A1 |
0.439 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251759 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 10980415 |
Since Sox9 also contains a potent transcription activation domain, it is a typical transcription factor. Two other members of the Sox family, L-Sox5 and Sox6, also bind to the 48-bp Col2a1 enhancer and together with Sox9 activate this enhancer as well as the endogenous Col2a1 |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
SOX5
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- 