4.0
Summary
| Name |  SOX11
|
| Full Name | Transcription factor SOX-11 |
| Synonyms | SOX11_HUMAN | |
| Primary ID | P35716 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Transcription factor that acts as a transcriptional activator (PubMed:24886874). Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity). Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron (By similarity). Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CHD8 | down-regulates quantity 
transcriptional regulation
|
SOX11 | 0.2 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | SOX11 | up-regulates quantity by expression 
transcriptional regulation
|
SPAST | 0.363 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | miR-508-5p | down-regulates quantity by destabilization
post transcriptional regulation
|
SOX11 | 0.4 |
| Publications: | 1 | Organism: | Homo Sapiens | |