Summary

Name LTBR
Full Name Tumor necrosis factor receptor superfamily member 3
Synonyms Lymphotoxin-beta receptor, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor type III, TNF-RIII, TNFR-III | D12S370, TNFCR, TNFR3, TNFRSF3
Primary ID P36941
Links - -
Type protein
Relations 6
Pathways NF-KB Non Canonical
Function Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding LTBR 0.95
Publications: 1 Organism: Homo Sapiens
Tissue: Ovary
Pathways:NF-KB Non Canonical
+ up-regulates img/indirect-activation.png unknown B Cell Maturation
Publications: 1 Organism: Homo Sapiens
Pathways:NF-KB Non Canonical
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation LTBR 0.53
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png unknown Lymphoma
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding LTBR 0.45
Publications: 1 Organism: Homo Sapiens
Tissue: Ovary
+ up-regulates activity img/direct-activation.png binding TRAF2 0.70
Publications: 1 Organism: Homo Sapiens
Pathways:NF-KB Non Canonical