Summary

Name SERPINB5
Full Name Serpin B5
Synonyms Maspin, Peptidase inhibitor 5, PI-5 | PI5
Primary ID P36952
Links - -
Type protein
Relations 3
Function Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation SERPINB5 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/direct_inhibition.png transcriptional regulation SERPINB5 0.425
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/direct_inhibition.png transcriptional regulation SERPINB5 0.417
Publications: 1