Summary

Name THPO
Full Name Thrombopoietin
Synonyms C-mpl ligand, ML, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand | MGDF
Primary ID P40225
Links - -
Type protein
Relations 1
Function Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding MPL 0.774
Publications: 1 Organism: Homo Sapiens