| + |
THPO | up-regulates 
binding
|
MPL |
0.783 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-113955 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11784712 |
Thrombopoietin(tpo) controls the formation of megakaryocytes and platelets from hematopoietic stem cells via activation of the c-mplreceptorand multiple downstream signal transduction pathways. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
GATA1 | up-regulates quantity by expression 
transcriptional regulation
|
MPL |
0.442 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254162 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15466856 |
Both Fli-1 and GATA-1 are required for formation of an active transcriptional complex on the C-MPL and GPIX promoters in vivo. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ATXN2L | down-regulates 
binding
|
MPL |
0.352 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-113891 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 11784712 |
A2d binds to cytokine receptors mpl and epo-r. A2d is associated with these unoccupied receptorsin vivo,and stimulation with tpo or epo causes the rapid dissociation of a2d from the activated receptor. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FLI1 | up-regulates quantity by expression
transcriptional regulation
|
MPL |
0.246 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254163 |
|
|
Homo sapiens |
MEG-01 Cell |
| pmid |
sentence |
| 15466856 |
Both Fli-1 and GATA-1 are required for formation of an active transcriptional complex on the C-MPL and GPIX promoters in vivo. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
MPL
- 
- 