4.0
Summary
| Name |  RGS2View Modifications |
| Full Name | Regulator of G-protein signaling 2 |
| Synonyms | RGS2, Cell growth-inhibiting gene 31 protein, G0/G1 switch regulatory protein 8 | G0S8 |
| Primary ID | P41220 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11063746, PubMed:19478087). It is involved in the negative regulation of the angiotensin-activated signaling pathway (PubMed:28784619). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (PubMed:19736320). |
phosphorylation