Summary

Name ASPA
Full Name Aspartoacylase
Synonyms Aminoacylase-2, ACY-2 | ACY2, ASP
Primary ID P45381
Links - -
Type protein
Relations 3
Pathways Aspartate and asparagine metabolism
Function Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids.

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Relations

Regulator Mechanism target score ℹ
+ ASPAdown-regulates quantity img/direct_inhibition.png chemical modification N-acetyl-L-aspartate(2-) 0.8
Publications: 1 Organism: Homo Sapiens
Pathways:Aspartate and asparagine metabolism
+ ASPAup-regulates quantity img/direct-activation.png chemical modification L-aspartate(1-) 0.8
Publications: 1 Organism: Homo Sapiens
Pathways:Aspartate and asparagine metabolism
+ ASPAup-regulates quantity img/direct-activation.png chemical modification acetic acid 0.8
Publications: 1 Organism: Homo Sapiens
Pathways:Aspartate and asparagine metabolism