Summary

Name KCNJ3
Full Name G protein-activated inward rectifier potassium channel 1
Synonyms GIRK-1, Inward rectifier K(+) channel Kir3.1, Potassium channel, inwardly rectifying subfamily J member 3 | GIRK1
Primary ID P48549
Links - -
Type protein
Relations 2
Function This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

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Modifications Tables

Relations

Regulator Mechanism target score
+ img/unknown.png phosphorylation KCNJ3 0.322
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding KCNJ5/KCNJ3 0.481
Publications: 1 Organism: Homo Sapiens
Tissue: Heart