3.0
Summary
| Name |  ACOT2
|
| Full Name | Acyl-coenzyme A thioesterase 2, mitochondrial |
| Synonyms | Acyl-CoA thioesterase 2, Acyl-coenzyme A thioester hydrolase 2a, CTE-Ia, Long-chain acyl-CoA thioesterase 2, ZAP128 | PTE2, PTE2A |
| Primary ID | P49753 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:16940157). Acyl-coenzyme A thioesterase 2/ACOT2 displays higher activity toward long chain acyl CoAs (C14-C20) (PubMed:16940157, PubMed:10944470). The enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria (By similarity). |
transcriptional regulation