| + |
MAPK1 | up-regulates 
phosphorylation
|
RGS19 |
0.488 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-129883 |
Ser151 |
EDYVSILsPKEVSLD |
Homo sapiens |
|
| pmid |
sentence |
| 15488168 |
Phosphorylation of gaip by erk2 were abrogated when serine at position 151 in the rgs domain was substituted by an alanine residue using site-directed mutagenesis. Furthermore, the lysosomal-autophagic pathway was not stimulated in s151a-gaip mutant-expressing cells when compared with wild-type gaip-expressing cells. These results demonstrate that the gtpase-activating protein activity of gaip is stimulated by erk2 phosphorylation. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-82083 |
Ser151 |
EDYVSILsPKEVSLD |
Homo sapiens |
|
| pmid |
sentence |
| 10993892 |
Phosphorylation of gaip by erk2 were abrogated when serine at position 151 in the rgs domain was substituted by an alanine residue using site-directed mutagenesis. Furthermore, the lysosomal-autophagic pathway was not stimulated in s151a-gaip mutant-expressing cells when compared with wild-type gaip-expressing cells. These results demonstrate that the gtpase-activating protein activity of gaip is stimulated by erk2 phosphorylation. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
CSNK2A2 |
phosphorylation
|
RGS19 |
0.333 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-251033 |
Ser24 |
ADRPPSMsSHDTASP |
in vitro |
|
| pmid |
sentence |
| 10760275 |
Phosphorylation was Mn(2+)-dependent, using both purified CK2 and CCVs. Ser-24 was identified as one of the phosphorylation sites. Our results establish that GAIP is phosphorylated and that only the membrane pool is phosphorylated, suggesting that GAIP can be regulated by phosphorylation events taking place at the level of clathrin-coated pits and vesicles. |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
CSNK2A1 |
phosphorylation
|
RGS19 |
0.334 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-250943 |
Ser24 |
ADRPPSMsSHDTASP |
in vitro |
|
| pmid |
sentence |
| 10760275 |
Phosphorylation was Mn(2+)-dependent, using both purified CK2 and CCVs. Ser-24 was identified as one of the phosphorylation sites. Our results establish that GAIP is phosphorylated and that only the membrane pool is phosphorylated, suggesting that GAIP can be regulated by phosphorylation events taking place at the level of clathrin-coated pits and vesicles. |
|
| Publications: |
1 |
Organism: |
In Vitro |
3.0
RGS19
- 
- 