3.0
Summary
| Name |  FABP6
|
| Full Name | Gastrotropin |
| Synonyms | GT, Fatty acid-binding protein 6, Ileal lipid-binding protein, ILBP, Intestinal 15 kDa protein, I-15P, Intestinal bile acid-binding protein, I-BABP | ILBP, ILLBP |
| Primary ID | P51161 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion (By similarity). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | FABP6 | up-regulates quantity 
relocalization
|
Fatty acid | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |