| + |
Fatty acid | up-regulates 
|
SIRT6 |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268156 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 25815987 |
Intriguingly, SIRT6 is chromatin bound, controls lipid metabolism, and is enzymatically activated by fatty acids |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FABP7 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264461 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SLC27A3 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264464 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SLC27A2 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264462 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FABP6 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264460 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FABP1 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264455 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
Fatty acid | up-regulates
|
PPARG |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-256189 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 29369787 |
Omega 3 fatty acids and fibrates are considered as natural and pharmacological ligands of PPARα, respectively, that reduce inflammation and arteriosclerosis in cardiovascular system |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | PPARgamma in cancer |
| + |
SLC27A1 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264463 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CD36 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264453 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SLC27A4 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264465 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FABP5 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264459 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SLC27A5 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264466 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FABP3 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264457 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SLC27A6 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264467 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FABP4 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264458 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
CAV1 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264454 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FABP2 | up-regulates quantity
relocalization
|
Fatty acid |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264456 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 28457600 |
Astrocytes and endothelial cells, two major components of the blood brain barrier, are the major contributors to the transportation of PUFAs from the circulation to brain. There are four classes of lipid transportation proteins involved in lipid synthesis and transportation in adult brain, including fatty acid translocase (FAT/CD36), caveolin-1, fatty acid binding proteins (FABPs) long chain acyl-coA synthase (ACS) and fatty acid transportation proteins (FATPs). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
Fatty acid