Summary

Name NR0B1
Full Name Nuclear receptor subfamily 0 group B member 1
Synonyms DSS-AHC critical region on the X chromosome protein 1, Nuclear receptor DAX-1 | AHC, DAX1
Primary ID P51843
Links - -
Type protein
Relations 4
Function Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity).

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Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png binding NR5A1 0.726
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by stabilization img/direct-activation.png monoubiquitination NR0B1 0.449
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/indirect_inhibition.png NR0B1 0.35
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding NCOR2 0.402
Publications: 1 Organism: Homo Sapiens