3.0
Summary
| Name |  HMGA2View Modifications |
| Full Name | High mobility group protein HMGI-C |
| Synonyms | High mobility group AT-hook protein 2 | HMGIC |
| Primary ID | P52926 |
| Links |  -  -  |
| Type | protein |
| Relations | 6 |
| Function | Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity). Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner (PubMed:28796236). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CDK1 | down-regulates 
phosphorylation
|
HMGA2 | 0.383 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | HMGA2 | down-regulates
binding
|
E4F1 | 0.379 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | HMGA2 | up-regulates quantity by expression 
transcriptional regulation
|
CCNA2 | 0.32 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | HMGA2 | up-regulates
|
Apoptosis | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | HMGA2 | down-regulates quantity by repression 
transcriptional regulation
|
SCNN1A | 0.2 |
| Publications: | 1 | Organism: | Rattus Norvegicus | |