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Summary
Name
MYOM2
View Modifications
Full Name
Myomesin-2
Synonyms
165 kDa connectin-associated protein, 165 kDa titin-associated protein, M-protein, Myomesin family member 2
Primary ID
P54296
Links
-
-
Type
protein
Relations
1
Function
Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.
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by mechanism
none
phosphorylation
by effect
none
down-regulates
by organism:
none
Homo sapiens
by tissue:
none
muscle
by cell-line
none
▶
Modifications Tables
MYOM2 as Target
Residue
Sequence
Modifier
Effect
Modification
Ser76
RVCAKRVsTQEDEEQ
PRKACA
inhibition
phosphorylation
Relations
Regulator
Mechanism
target
score
ℹ
+
PRKACA
down-regulates
phosphorylation
MYOM2
0.2
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-56395
Ser76
RVCAKRVsTQEDEEQ
Homo sapiens
pmid
sentence
9529381
This binding is regulated in vitro by phosphorylation of a single serine residue (ser76) in the immediately adjacent amino-terminal domain mp1. M-protein phosphorylation by camp-dependent kinase a inhibits binding to myosin lmm.
Publications:
1
Organism:
Homo Sapiens
Tissue:
Muscle