Summary

Name NRL
Full Name Neural retina-specific leucine zipper protein
Synonyms NRL | D14S46E
Primary ID P54845
Links - -
Type protein
Relations 3
Function Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B (PubMed:21981118). Functions also as a transcriptional coactivator, stimulating transcription mediated by the transcription factor CRX and NR2E3 (PubMed:17335001). Binds in a sequence-specific manner to the rhodopsin promoter (PubMed:17335001).

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding NRL 0.568
Publications: 1 Organism: Bos Taurus
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation RBP3 0.383
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation RHO 0.456
Publications: 1 Organism: Homo Sapiens