3.0
Summary
| Name |  AQP5View Modifications |
| Full Name | Aquaporin-5 |
| Synonyms | AQP-5 | |
| Primary ID | P55064 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Forms a water-specific channel (PubMed:8621489, PubMed:18768791). Plays an important role in fluid secretion in salivary glands (By similarity). Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells (PubMed:16571723). Seems to play a redundant role in water transport in the eye, lung and in sweat glands (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PRKACA | up-regulates activity 
phosphorylation
|
AQP5 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PKA | up-regulates activity
phosphorylation
|
AQP5 | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | AQP5 | up-regulates activity
binding
|
CyclinD/CDK4 | 0.249 |
| Publications: | 1 | |||