+ |
RORA | up-regulates quantity by expression
transcriptional regulation
|
CAV3 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254255 |
|
|
Mus musculus |
|
pmid |
sentence |
15199055 |
Furthermore, we show that the muscle carnitine palmitoyltransferase-1 and caveolin-3 promoters are directly regulated by ROR and coactivated by p300 and PGC-1. This study implicates RORs in the control of lipid homeostasis in skeletal muscle. |
|
Publications: |
1 |
Organism: |
Mus Musculus |
+ |
EP300 | up-regulates quantity by expression
transcriptional regulation
|
CAV3 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254259 |
|
|
Chlorocebus aethiops |
COS-1 Cell |
pmid |
sentence |
15199055 |
Furthermore, we show that the muscle carnitine palmitoyltransferase-1 and caveolin-3 promoters are directly regulated by ROR and coactivated by p300 and PGC-1. This study implicates RORs in the control of lipid homeostasis in skeletal muscle. |
|
Publications: |
1 |
Organism: |
Chlorocebus Aethiops |
+ |
CAV3 | form complex
binding
|
DGC |
0.496 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-255997 |
|
|
Homo sapiens |
|
pmid |
sentence |
15117830 |
The DGC is composed of dystrophin (blue), an elongated cytoskeletal protein that links to cytoplasmic γ-actin and the transmembrane components of the DGC. Dystrophin binds to the tail of β-dystroglycan (orange). Dystroglycan is composed of 2 subunits, α and β, each produced from the same gene. Dystroglycan binds to the extracellular matrix protein laminin-α2. The sarcoglycan complex (blue-green) is composed of multiple subunits. Mutations in the genes encoding α-, β-, γ-, and δ-sarcoglycan lead to a similar phenotype as dystrophin mutations and include cardiomyopathy and muscular dystrophy in humans and mice. Additional subcomplexes in the DGC in skeletal muscle include α and β dystrobrevin, the syntrophins, nNOS, and caveolin 3 (pink). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
PPARGC1A | up-regulates quantity by expression
transcriptional regulation
|
CAV3 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-254261 |
|
|
Chlorocebus aethiops |
COS-1 Cell |
pmid |
sentence |
15199055 |
Furthermore, we show that the muscle carnitine palmitoyltransferase-1 and caveolin-3 promoters are directly regulated by ROR and coactivated by p300 and PGC-1. This study implicates RORs in the control of lipid homeostasis in skeletal muscle. |
|
Publications: |
1 |
Organism: |
Chlorocebus Aethiops |