Summary

Name CORO7
Full Name Coronin-7
Synonyms Crn7, 70 kDa WD repeat tumor rejection antigen homolog |
Primary ID P57737
Links - -
Type protein
Relations 1
Function F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology. {ECO:0000269|PubMed:16905771, ECO:0000269|PubMed:24768539}.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation CORO7 0.344
Publications: 1 Organism: In Vitro