| + |
CTNNB1 | up-regulates quantity by expression 
transcriptional regulation
|
CLDN2 |
0.312 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254114 |
|
|
Mus musculus |
C57MG Cell |
| pmid |
sentence |
| 14751232 |
Furthermore, claudin-2 promoter activity was found to be enhanced by the TCF-4/beta-catenin transcription complex. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
LEF1 | up-regulates quantity by expression
transcriptional regulation
|
CLDN2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-254120 |
|
|
Mus musculus |
C57MG Cell |
| pmid |
sentence |
| 14751232 |
Activity of the claudin-2 promoter was elevated in mouse mammary epithelial C57 cells expressing Wnt-1. LEF-1, a nuclear effector of the Wnt signaling pathway which is involved in the regulation of cell differentiation and polarization, was found to bind directly to the claudin-2 promoter as revealed by electrophoretic mobility shift assays. Expression of LEF-1 and beta-catenin both enhanced claudin-2 promoter activity. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
3.0
CLDN2
- 
- 