Summary

Name SEC61B
Full Name Protein transport protein Sec61 subunit beta
Synonyms SC61B_HUMAN |
Primary ID P60468
Links - -
Type protein
Relations 1
Function Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER) (PubMed:12475939). Component of a ribosome-associated ER translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis (PubMed:32820719). The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER (PubMed:19121997). Required for PKD1/Polycystin-1 biogenesis (By similarity).

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Relations

Regulator Mechanism target score ℹ
+ SEC61Bform complex img/form-complex.png binding SEC61 complex 0.905
Publications: 1 Organism: In Vitro