| + |
SEC61 complex | up-regulates quantity 
relocalization
|
calcium(2+) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265284 |
|
|
|
|
| pmid |
sentence |
| 33925740 |
The Sec61 complex in the ER membrane represents the major entry point for precursor polypeptides into the membrane or lumen of the ER and provides a conduit for Ca2+ ions from the ER lumen to the cytosol. |
|
| Publications: |
1 |
| + |
SEC61 complex | up-regulates activity
binding
|
SEC62 |
0.748 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265275 |
|
|
|
|
| pmid |
sentence |
| 33925740 |
This is where allosteric effectors of the Sec61 complex (BiP together with Sec62/Sec63 complex or TRAP complex) (Figure 2 and Figure 5) and auxiliary membrane protein insertases (EMC and TMCO1 complex) join the game |
|
| Publications: |
1 |
| + |
SEC61 complex | up-regulates activity
binding
|
HSPA5 |
0.452 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265276 |
|
|
|
|
| pmid |
sentence |
| 33925740 |
This is where allosteric effectors of the Sec61 complex (BiP together with Sec62/Sec63 complex or TRAP complex) (Figure 2 and Figure 5) and auxiliary membrane protein insertases (EMC and TMCO1 complex) join the game |
|
| Publications: |
1 |
| + |
SEC61G | form complex 
binding
|
SEC61 complex |
0.892 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265278 |
|
|
in vitro |
|
| pmid |
sentence |
| 33925740 |
The heterotrimeric Sec61 complex of the ER membrane represents the major entry point for precursor polypeptides into the membrane or lumen of the ER |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
SEC61 complex | up-regulates activity
binding
|
SEC63 |
0.891 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265274 |
|
|
|
|
| pmid |
sentence |
| 33925740 |
This is where allosteric effectors of the Sec61 complex (BiP together with Sec62/Sec63 complex or TRAP complex) (Figure 2 and Figure 5) and auxiliary membrane protein insertases (EMC and TMCO1 complex) join the game |
|
| Publications: |
1 |
| + |
SEC61A2 | form complex
binding
|
SEC61 complex |
0.654 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267728 |
|
|
in vitro |
|
| pmid |
sentence |
| 33925740 |
The heterotrimeric Sec61 complex of the ER membrane represents the major entry point for precursor polypeptides into the membrane or lumen of the ER |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
SEC61A1 | form complex
binding
|
SEC61 complex |
0.765 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265279 |
|
|
in vitro |
|
| pmid |
sentence |
| 33925740 |
The heterotrimeric Sec61 complex of the ER membrane represents the major entry point for precursor polypeptides into the membrane or lumen of the ER |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
SEC61B | form complex
binding
|
SEC61 complex |
0.908 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265277 |
|
|
in vitro |
|
| pmid |
sentence |
| 33925740 |
The heterotrimeric Sec61 complex of the ER membrane represents the major entry point for precursor polypeptides into the membrane or lumen of the ER |
|
| Publications: |
1 |
Organism: |
In Vitro |
3.0
SEC61 complex