Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-246707 |
Ser3 |
sGVQVADE |
Homo sapiens |
Testis |
pmid |
sentence |
11418599 |
The present study provides evidence that TESK2 can phosphorylate cofilin and ADF specifically at Ser-3. Since actin-depolymerizing and -severing activities of cofilin/ADF are abrogated by phosphorylation at Ser-3, TESK2 seems to play an important role in actin filament dynamics by inhibiting cofilin/ADF activity. |
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