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Summary
Name
RND3
View Modifications
Full Name
Rho-related GTP-binding protein RhoE
Synonyms
Protein MemB, Rho family GTPase 3, Rho-related GTP-binding protein Rho8, Rnd3 | ARHE, RHO8, RHOE
Primary ID
P61587
Links
-
-
Type
protein
Relations
1
Function
Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
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by mechanism
none
phosphorylation
by effect
none
up-regulates
by organism:
none
Homo sapiens
by tissue:
none
by cell-line
none
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Modifications Tables
RND3 as Target
Residue
Sequence
Modifier
Effect
Modification
Ser11
RRASQKLsSKSIMDP
ROCK1
activation
phosphorylation
Relations
Regulator
Mechanism
target
score
ℹ
+
ROCK1
up-regulates
phosphorylation
RND3
0.731
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-134703
Ser11
RRASQKLsSKSIMDP
Homo sapiens
pmid
sentence
15775972
We show that rock phosphorylates endogenous rhoe at serine 11 upon cell stimulation with platelet-derived growth factor. Phosphorylation has no effect on rhoe binding to rock i, but instead increases rhoe protein stability.
Publications:
1
Organism:
Homo Sapiens