+ |
DCAF7 | up-regulates activity
binding
|
DYRK1A |
0.733 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-260630 |
|
|
Chlorocebus aethiops |
COS-7 Cell |
pmid |
sentence |
14593110 |
Two isoforms of DYRK, DYRK1A and DYRK1B, co-immunoprecipitate with HAN11 when coexpressed in COS cells indicating that the proteins interact in mammalian cells. HAN11 might target DYRKs to cytosolic locations for regulation of specific cellular functions. |
|
Publications: |
1 |
Organism: |
Chlorocebus Aethiops |
+ |
DCAF7 | down-regulates quantity by repression
transcriptional regulation
|
GLI1 |
0.263 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-260634 |
|
|
Homo sapiens |
HEK-293T Cell, SZ-95 Cell |
pmid |
sentence |
16887337 |
HAN11 and mDia1 repressed DYRK1A-dependent GLI1 transcriptional activity. The studies of SZ95 cells suggest that HAN11 reduces GLI1-dependent transcription by decreasing the nuclear pool of GLI1. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
DCAF7 | up-regulates activity
binding
|
DYRK1B |
0.752 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-260631 |
|
|
Chlorocebus aethiops |
COS-7 Cell |
pmid |
sentence |
14593110 |
Two isoforms of DYRK, DYRK1A and DYRK1B, co-immunoprecipitate with HAN11 when coexpressed in COS cells indicating that the proteins interact in mammalian cells. HAN11 might target DYRKs to cytosolic locations for regulation of specific cellular functions. |
|
Publications: |
1 |
Organism: |
Chlorocebus Aethiops |