Summary

Name KCNJ2
Full Name Inward rectifier potassium channel 2
Synonyms Cardiac inward rectifier potassium channel, Inward rectifier K(+) channel Kir2.1, IRK-1, hIRK1, Potassium channel, inwardly rectifying subfamily J member 2 | IRK1
Primary ID P63252
Links - -
Type protein
Relations 2
Function Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation KCNJ2 0.2
Publications: 1 Organism: In Vitro
+ down-regulates activity img/direct_inhibition.png phosphorylation KCNJ2 0.2
Publications: 1 Organism: In Vitro