+ |
IL13 | up-regulates
binding
|
IL13RA1 |
0.847 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-100750 |
|
|
Homo sapiens |
T-lymphocyte, Macrophage, Monocyte |
pmid |
sentence |
12704343 |
It is now known that this alternate receptor is a heterodimer, the type ii il-4 receptor or the il-13 receptor, which is comprised of IL-4R And IL-13R1. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Tissue: |
Muscle, Lung, Smooth Muscle |
+ |
IL4 | up-regulates
binding
|
IL13RA1 |
0.772 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-100759 |
|
|
Homo sapiens |
T-lymphocyte, Macrophage, Monocyte |
pmid |
sentence |
12704343 |
It is now known that this alternate receptor is a heterodimer, the type ii il-4 receptor or the il-13 receptor, which is comprised of IL-4R And IL-13R1. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Tissue: |
Muscle, Lung, Smooth Muscle |
+ |
IL13RA1 | up-regulates
binding
|
TYK2 |
0.547 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-100756 |
|
|
Homo sapiens |
T-lymphocyte, Macrophage, Monocyte |
pmid |
sentence |
12704343 |
IL-4R, ?c, and IL-13R1 All contain proline-rich box-1 regions that bind jak1, jak3, and tyk2, respectivelyil-4 uses the type ii receptor, and IL-13R1 Binds tyk2. Il-13 results in activation of jak1 and tyk2 in hematopoietic and nonhematopoietic cells. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
Tissue: |
Muscle, Lung, Smooth Muscle |