3.0
Summary
| Name |  GPSM2View Modifications |
| Full Name | G-protein-signaling modulator 2 |
| Synonyms | Mosaic protein LGN | LGN |
| Primary ID | P81274 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Plays an important role in mitotic spindle pole organization via its interaction with NUMA1 (PubMed:11781568, PubMed:15632202, PubMed:21816348). Required for cortical dynein-dynactin complex recruitment during metaphase (PubMed:22327364). Plays a role in metaphase spindle orientation (PubMed:22327364). Plays also an important role in asymmetric cell divisions (PubMed:21816348). Has guanine nucleotide dissociation inhibitor (GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity (By similarity). |
phosphorylation