3.0
Summary
| Name |  HSPG2
|
| Full Name | Basement membrane-specific heparan sulfate proteoglycan core protein |
| Synonyms | HSPG, Perlecan, PLC |
| Primary ID | P98160 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development.; FUNCTION |
binding