Summary

Name PPP2R2B
Full Name Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Synonyms PP2A subunit B isoform B55-beta, PP2A subunit B isoform PR55-beta, PP2A subunit B isoform R2-beta, PP2A subunit B isoform beta
Primary ID Q00005
Links - -
Type protein
Relations 2
Function The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding PP2Ca_R1A_Bd 0.752
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding PDPK1 0.336
Publications: 1 Organism: Homo Sapiens