Summary

Name U2AF1
Full Name Splicing factor U2AF 35 kDa subunit
Synonyms U2 auxiliary factor 35 kDa subunit, U2 small nuclear RNA auxiliary factor 1, U2 snRNP auxiliary factor small subunit | U2AF35, U2AFBP
Primary ID Q01081
Links - -
Type protein
Relations 1
Function Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.

Viewer

Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding U2AF1/U2AF2
Publications: 1 Organism: Homo Sapiens