Name U2AF1
Full Name Splicing factor U2AF 35 kDa subunit
Synonyms U2 auxiliary factor 35 kDa subunit, U2 small nuclear RNA auxiliary factor 1, U2 snRNP auxiliary factor small subunit | U2AF35, U2AFBP
Primary ID Q01081
Links - -
Type protein
Relations 1
Function Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.



Regulator Mechanism target score
+ form complex img/form-complex.png binding U2AF1/U2AF2 0.14
Publications: 1 Organism: Homo Sapiens