3.0
Summary
| Name |  U2AF1
|
| Full Name | Splicing factor U2AF 35 kDa subunit |
| Synonyms | U2 auxiliary factor 35 kDa subunit, U2 small nuclear RNA auxiliary factor 1, U2 snRNP auxiliary factor small subunit | U2AF35, U2AFBP |
| Primary ID | Q01081 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron. |
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binding
transcriptional regulation