| + |
CDX2 | up-regulates quantity by expression
transcriptional regulation
|
MUC2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253966 |
|
|
Chlorocebus aethiops |
COS Cell |
| pmid |
sentence |
| 12559945 |
COS-7 cells were transiently transfected with a CDX1 or CDX2 expression construct and then used for the luciferase assay, reverse transcription-polymerase chain reaction, and electrophoretic mobility shift assay (EMSA). The CDX2 expression construct activated the MUC2 promoter and increased the endogenous MUC2 mRNA level, while the CDX1 one did not. |
|
| Publications: |
1 |
Organism: |
Chlorocebus Aethiops |
| + |
ATOH1 | up-regulates quantity by expression
transcriptional regulation
|
MUC2 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253755 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 17000673 |
This study confirms the importance of HATH1 for the development of intestinal secretory cells. The results further suggest that HATH1 is an important factor in the up-regulation of MUC2 expression that occurs in mucinous cancers and signet ring carcinomas. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |