Summary

Name ATOH1
Full Name Protein atonal homolog 1
Synonyms Class A basic helix-loop-helix protein 14, bHLHa14, Helix-loop-helix protein hATH-1, hATH1 | ATH1, BHLHA14
Primary ID Q92858
Links - -
Type protein
Relations 5
Function Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity).

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates quantity img/direct-activation.png phosphorylation ATOH1 0.346
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation HES6 0.452
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation ATOH1 0.417
Publications: 1 Organism: Mus Musculus
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation ATOH1 0.485
Publications: 1 Organism: Mus Musculus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation MUC2 0.2
Publications: 1 Organism: Homo Sapiens