3.0
Summary
| Name |  CREMView Modifications |
| Full Name | cAMP-responsive element modulator |
| Synonyms | Inducible cAMP early repressor, ICER |
| Primary ID | Q03060 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation (PubMed:10373550). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | MAPK3 | down-regulates quantity by destabilization 
phosphorylation
|
CREM | 0.421 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | CDK1 | down-regulates quantity by destabilization
phosphorylation
|
CREM | 0.299 |
| Publications: | 1 | Organism: | Mus Musculus | |
| + | FHL5 | up-regulates activity 
binding
|
CREM | 0.649 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CREM | down-regulates quantity by repression
transcriptional regulation
|
IL2 | 0.499 |
| Publications: | 1 | Organism: | Homo Sapiens | |