Summary

Name TLE3
Full Name Transducin-like enhancer protein 3
Synonyms Enhancer of split groucho-like protein 3, ESG3 | KIAA1547
Primary ID Q04726
Links - -
Type protein
Relations 1
Function Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).

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Relations

Regulator Mechanism target score ℹ
+ PHF12up-regulates activity img/direct-activation.png binding TLE3 0.2
Publications: 1 Organism: Homo Sapiens