3.0
Summary
| Name |  APLP2View Modifications |
| Full Name | Amyloid-like protein 2 |
| Synonyms | APLP-2, APPH, Amyloid protein homolog, CDEI box-binding protein, CDEBP | APPL2 |
| Primary ID | Q06481 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PRKCA |
phosphorylation
|
APLP2 | 0.346 |
| Publications: | 1 | Organism: | In Vitro | |
| + | MAPK8 | up-regulates 
phosphorylation
|
APLP2 | 0.37 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | CDK1 |
phosphorylation
|
APLP2 | 0.338 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Tissue: | Brain | |||