Relation Results

Summary

Name SOS2
Full Name Son of sevenless homolog 2
Synonyms SOS-2
Primary ID Q07890
Links - -
Type protein
Relations 3
Function Promotes the exchange of Ras-bound GDP by GTP.

Viewer

Type: Score: Layout: SPV 
0.7820.7050.876SOS2HRASKRASGRB2

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations
Regulator
Mechanism
target
score ℹ
+ SOS2up-regulates img/direct-activation.png guanine nucleotide exchange factor HRAS 0.782
Identifier Residue Sequence Organism Cell Line
SIGNOR-175262 Homo sapiens
pmid sentence
Grb2 binds and activates sos, which then activates ras, and this activates p110 independently of p85.
Publications: 1 Organism: Homo Sapiens
+ SOS2up-regulates img/direct-activation.png guanine nucleotide exchange factor KRAS 0.705
Identifier Residue Sequence Organism Cell Line
SIGNOR-175265 Homo sapiens
pmid sentence
Grb2 binds and activates sos, which then activates ras, and this activates p110 independently of p85.
Publications: 1 Organism: Homo Sapiens
+ GRB2up-regulates img/direct-activation.png binding SOS2 0.876
Identifier Residue Sequence Organism Cell Line
SIGNOR-175180 Homo sapiens
pmid sentence
Grb2 binds and activates sos, which then activates ras, and this activates p110 independently of p85.
Publications: 1 Organism: Homo Sapiens
a simple tooltip