3.0
Summary
| Name |  LAMTOR4
|
| Full Name | Ragulator complex protein LAMTOR4 |
| Synonyms | Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4 | C7orf59 |
| Primary ID | Q0VGL1 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. |
binding