| + |
KIF5A | up-regulates 
|
Plus-end directed sliding movement |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272523 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 19773780 |
In general, N-kinesins and C-kinesins drive microtubule plus end- and minus end-directed motilities, respectively, and M-kinesins depolymerize microtubules1,9 (Box 1).|Forty-five genes that encode kinesin superfamily proteins (also known as KIFs) have been discovered in the mouse and human genomes.|KIFs are molecular motors that directionally transport various cargos, including membranous organelles, protein complexes and mRNAs, along the microtubule system. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
KIF5A | up-regulates
|
Organelle_transport |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264067 |
|
|
Homo sapiens |
Neuron |
| pmid |
sentence |
| 9438838 |
The kinesin superfamily of proteins plays a major role in this complex organelle transport. Kinesin is primarily associated with anterogradely transported membranous organelles in nerve axons. KIF5B and HsuKHC are expressed ubiquitously in many tissues, whereas KIF5A, KIF5C, and HsnKHC are specific to nerve tissue. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
KIF5A | up-regulates activity 
binding
|
DLG4 |
0.319 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-264065 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 31753031 |
Postsynaptic density protein 95 (PSD-95) is transported by KIF5 to dendritic regions |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
KIF5A
- 
- 